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Wegener’s Granulomatosis

Inpatient Management Guide Definition Vasculitis Vasculitis, in its strictest sense, refers to inflammation of blood vessel walls that results in vessel narrowing, occlusion, aneurysm and/or rupture. The vasculitides are syndromes characterized by the presence of vasculitis; these are categorized according to size of the blood vessel involved Large vessel vasculitis: giant cell arteritis (GCA) and … Read more

Vasculitis

Inpatient Management Guide Definition Vasculitis Vasculitis, in its strictest sense, refers to inflammation of blood vessel walls that results in vessel narrowing, occlusion, aneurysm and/or rupture. The vasculitides are syndromes characterized by the presence of vasculitis; these are categorized according to size of the blood vessel involved Large vessel vasculitis: giant cell arteritis (GCA) and … Read more

Systemic Lupus Erythematosis

Inpatient Management Guide Definition SLICC Criteria: Must satisfy 4 of the clinical and immunologic criteria including: at least one clinical criterion and one immunological criterion OR biopsy proven nephritis compatible with SLE in the presence of positive ANA or dsDNA antibodies Clinical: Acute cutaneous lupus: includes malar rash, bullous lupus, toxic epidermal necrolysis variant of … Read more

SLE

Inpatient Management Guide Definition SLICC Criteria: Must satisfy 4 of the clinical and immunologic criteria including: at least one clinical criterion and one immunological criterion OR biopsy proven nephritis compatible with SLE in the presence of positive ANA or dsDNA antibodies Clinical: Acute cutaneous lupus: includes malar rash, bullous lupus, toxic epidermal necrolysis variant of … Read more

Scleroderma

Inpatient Management Guide Definition 2013 ACR/EULAR criteria for Systemic Sclerosis Item Subitem Weight/Score Skin thickening of the fingers of both hands extending proximally to the MCP (this alone is sufficient to make the diagnosis)   9 Skin thickening of the fingers (highest of the two) Puffy fingers 2   Sclerodactyly of the fingers 4 Fingertip … Read more

Sarcoidosis

Inpatient Management Guide Definition Systemic disease defined by hallmark finding of non-caseating granulomas on biopsy + clinical findings and imaging consistent with sarcoidosis. Exclude other causes of granuloma formation. Etiology Poorly understood but thought to be related to interactions between specific genetic factors such as HLA class II antigens (i.e. HLA-DRB1, HLA-DRQ1) and antigen exposure … Read more

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